Application of Real-Time Shear Wave Elastography in The Evaluation of Acute Hepatitis After Treatment

Abstract

Zhiqun Bai, Delong Jiang, Xuemei Wang, Zhen Zhang

Purpose: To evaluate the elasticity modulus value of different stages and types of acute liver hepatitis after treatment by real-time shear wave elastography (SWE) technology. Methods: Patients with a clinical diagnosis of acute hepatitis undergoing ultrasonography (US) and SWE were selected for the study, including those with drug-induced hepatitis, autoimmune hepatitis, and viral hepatitis. The elastic modulus values of three groups were measured before treatment and 1 month and 3 months after treatment, separately, and were statistically analyzed.
Results: A total of 45 patients were selected for the study, including those with drug-induced hepatitis (n = 17), autoimmune hepatitis (n = 8), and viral hepatitis (n = 20). The average elastic modulus values of three groups before treatment were 26.248 ± 7.837kPa, 14.670 ± 3.945kPa, and 23.860 ± 6.928kPa, respectively. After treatment for 1 month and 3 months, the mean modulus values of three groups decreased and have a statistically difference compared with that before treatment (P < 0.05). The mean elastic modulus value in autoimmune hepatitis group was statistically significant from those before treatment in the other two groups, respectively (P < 0.05). The mean elastic modulus value in viral hepatitis group was statistically significant from that 1 month after treatment in the other two groups, respectively (P < 0.05). The mean elastic modulus value in three groups after 3 months of treatment was not statistically significant (P > 0.05).
Conclusion: SWE can be used to differentiate between different stages and types of acute hepatitis before and after treatment.

PDF