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Toxicology and Applied Pharmacology Insights(TAPI)

ISSN: 2641-0451 | DOI: 10.33140/TAPI

Sinonasal Inverted Papilloma: Epidemiological and Pathological Profile from 15 Cases

Abstract

I Boujguenna, S Elhatimy, N Mansouri, Y Rochdi, H Nouri, A Raji, CH.Bouyaali, N Cherif Gannoun Idrissi, A Fakhri1 and H Rais

Inverted papilloma is a rare benign Sino nasal tumor marked by strong local aggressiveness, a high rate of recurrence after surgery and an unpredictable risk of association with squamous cell carcinoma. We retrospectively investigated 15 cases of inverted papilloma that were treated between January 2004 and December 2018, diagnosed at the pathological anatomy department, CHU MOHAMMED VI of Marrakech. The objective of this work was to study the epidemiological and anatomopathological profile of these polyps. The sex ratio of 2.75 was clearly predominate in males with an average age of 40 years. Its main clinical symptoms was manifested by nasal blockage. The radiological assessment using CT and nasosinus MRI couple constituted a very important means of the positive diagnosis of the inverted papilloma and of the choice of the operating method. Histological examination showed a papillomata’s polypoid respiratory mucosa, at the level of the chorion, with signs of low grade dysplasia in only one case. Their high potential for local aggressiveness, the fear of a recurrence and the possibility of the occurrence of a malignant tumor require radical management.

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