Rapid On-site Evaluation (ROSE) for Diagnosing Bone Pathologies: A Narrative Review

Abstract

Dr. Mohit Dhingra, Dr. Anil Regmi, Dr. Kranthi Kumar Jandrasupalli, Dr. Prashant Joshi, Dr. Bishwa Bandhu Niraula

Infective or neoplastic bone lesion needs radiological and histological correlation for the diagnosis. Bone needs to be decalcified so the process is time-consuming. The quality and quantity of biopsy material taken need evaluation in order to avoid false-negative results and delay in diagnosis. This study aims to study the utility of ROSE, its background, pro- cess, and interpretation for different bone lesions.

ROSE can be considered a useful tool to identify false negative benign cases and true positive malignant cases. The use of this technique can save the turnaround time for the bone biopsy report and help in treating patients with malignant bone tumors more aggressively and appropriately. This in turn will benefit the outcome of the patients in terms of mor- bidity and mortality in rapidly growing lesions and the overall survival of the patients.

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