Advances In Therapeutic Use of Microfluidics (Body on A Chip): A Review

Abstract

Kulvinder Kochar Kaur, Gautam Allahbadia and Mandeep Singh

Microfluidic technology with the advancement in biosensor technologyhas reached the arena of hospital set up lead- ing to improvement in diagnostic as well as therapeutic fields with respect to various analytes,drug metabolites,deliv- ery of drugs.Further enhancement has resulted in developments of cellular constructs right from tissues and various organs in the form of ‘’heart on a chip’’,or any organ on a chip’’ which involves any system of the body be it CVS,re- spiratory system,nervous,excretory ,digestive,skin or reproductive system both mimicking the normal physiology as well as pathologies which makes it easier to use it in the field oftreating any diseases as well as treating various cancers and testing the side effects of any drugs before delivering with cutting the cost on animal studies,since these BioMEMS have started becoming cheaper utilizing nano litres of the reagent and capacity to carry out umpteen tests in smaller volumes of samples and reagents.This review basically goes into the detail of organ on chipor biological /biomedical microelectrico-mechanical systems(BioMEMS)in medicinewith respect to different tissue engineering projects be it tissue transplantation or discovering newer drugs for treating cancer.

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