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Pharmacogenomics Articles Open Access

Pharmacogenomics is the examine of ways genes affect a individual’s response to drugs. This tremendously new area combines pharmacology and genomics to develop effective, secure medicines and doses to be able to be tailor-made to a character’s genetic makeup. Many drugs that are currently to be had are “one size fits all,” but they do not work the same manner for everyone. It can be tough to are expecting who will advantage from a medication, who will no longer reply at all, and who will revel in negative facet effects. Adverse drug reactions are a considerable reason of hospitalizations and deaths within the United States. With the knowledge gained from the Human Genome Project, researchers are getting to know how inherited differences in genes have an effect on the body’s response to medications. These genetic differences might be used to predict whether a medication might be effective for a particular man or woman and to help prevent detrimental drug reactions. Conditions that affect a man or woman’s reaction to positive drugs encompass clopidogrel resistance, warfarin sensitivity, warfarin resistance, malignant hyperthermia, Stevens-Johnson syndrome/toxic epidermal necrolysis, and thiopurine S-methyltransferase deficiency.

Last Updated on: May 20, 2024

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