An enzyme biosensor is an analytical device that combines an enzyme with a transducer to produce a signal proportional to target analyte concentration. ... The coupling of enzymes with electrochemical sensors permits the simple determination of metabolites, therapeutic drugs, antigens, and antibodies. Biosensors and their role in medical science including early stage detection of human interleukin-10 causing heart diseases, rapid detection of human papilloma virus, etc. are important aspects. Fluorescent biosensors play a vital role in drug discovery and in cancer. Biosensors are devices comprising a biological element and a physiochemical detector that are used to detect analytes. These instruments have a wide range of applications ranging from clinical through to environmental and agricultural. The devices are also used in the food industry.